Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism

Author:

Shilkaitis Anne,Green Albert,Punj Vasu,Steele Vernon,Lubet Ronald,Christov Konstantin

Publisher

Springer Science and Business Media LLC

Reference28 articles.

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3. Dorgan JF, Stanczyk FZ, Longscope C, Stephenson HE, Chang L, Miller R, Franz C, Falk RT, Kahle L: Relationship of serum dehydroepiandrosterone (DHEA) dehydroepiandrosterone sulfate and 5-androstene-β, 17-β-diol to risk of breast cancer in postmenopausal women. Cancer Epidemiol Biomark Prev. 1997, 6: 177-181.

4. Ratko TA, Detrisac CJ, Mehta RG, Kelloff GJ, Moon RC: Inhibition of rat mammary gland chemical carcinogenesis by dietary dehydroepindrosterone or a fluorinated analogue dehydroepiandrosterone. Cancer Res. 1991, 51: 481-486.

5. Li S, Yan XX, Belanger A, Labrie F: Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by DMBA in the rat. Breast Cancer Res Treat. 1994, 29: 203-217. 10.1007/BF00665681.

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