Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype

Author:

Benedictus Lindert,Otten Henny G,van Schaik Gerdien,van Ginkel Walter GJ,Heuven Henri CM,Nielen Mirjam,Rutten Victor PMG,Koets Ad P

Publisher

Springer Science and Business Media LLC

Subject

General Veterinary

Reference40 articles.

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2. Jones BA, Sauter-Louis C, Henning J, Stoll A, Nielen M, Van Schaik G, Smolenaars A, Schouten M, den Uijl I, Fourichon C, Guatteo R, Madouasse A, Nusinovici S, Deprez P, De Vliegher S, Laureyns J, Booth R, Cardwell JM, Pfeiffer DU: Calf-level factors associated with bovine neonatal pancytopenia - a multi-country case–control study. PLoS ONE. 2013, 8: e80619-10.1371/journal.pone.0080619.

3. Pardon B, Steukers L, Dierick J, Ducatelle R, Saey V, Maes S, Vercauteren G, De Clercq K, Callens J, De Bleecker K, Deprez P: Haemorrhagic diathesis in neonatal calves: an emerging syndrome in Europe. Transbound Emerg Dis. 2010, 57: 135-146. 10.1111/j.1865-1682.2010.01098.x.

4. Bell CR, Rocchi MS, Dagleish MP, Melzi E, Ballingall KT, Connelly M, Kerr MG, Scholes SF, Willoughby K: Reproduction of bovine neonatal pancytopenia (BNP) by feeding pooled colostrum reveals variable alloantibody damage to different haematopoietic lineages. Vet Immunol Immunopathol. 2013, 151: 303-314. 10.1016/j.vetimm.2012.12.002.

5. Kappe EC, Halami MY, Schade B, Alex M, Hoffmann D, Gangl A, Meyer K, Dekant W, Schwarz BA, Johne R, Buitkamp J, Böttcher J, Müller H: Bone marrow depletion with haemorrhagic diathesis in calves in Germany: characterization of the disease and preliminary investigations on its aetiology. Berl Munch Tierarztl Wochenschr. 2010, 123: 31-41.

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