Deep sequencing of multiple regions of glial tumors reveals spatial heterogeneity for mutations in clinically relevant genes

Author:

Kumar Akash,Boyle Evan A,Tokita Mari,Mikheev Andrei M,Sanger Michelle C,Girard Emily,Silber John R,Gonzalez-Cuyar Luis F,Hiatt Joseph B,Adey Andrew,Lee Choli,Kitzman Jacob O,Born Donald E,Silbergeld Daniel L,Olson James M,Rostomily Robert C,Shendure Jay

Publisher

Springer Science and Business Media LLC

Reference15 articles.

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3. Sottoriva A, Spiteri I, Piccirillo SG, Touloumis A, Collins VP, Marioni JC, Curtis C, Watts C, Tavare S: Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci U S A. 2013, 110: 4009-4014. 10.1073/pnas.1219747110.

4. Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, Akhavanfard S, Cahill DP, Aldape KD, Betensky RA, Louis DN, Iafrate AJ: Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell. 2011, 20: 810-817. 10.1016/j.ccr.2011.11.005.

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