A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators-Reference-Cited by-同舟云学术

A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

Published:2014-07 Issue:7 Volume:15 Page:
ISSN:1474-760X
Container-title:Genome Biology
language:en
Short-container-title:Genome Biol

Author:

Hurst Laurence D, ,Sachenkova Oxana,Daub Carsten,Forrest Alistair RR,Huminiecki Lukasz

Publisher

Springer Science and Business Media LLC

Link

http://link.springer.com/content/pdf/10.1186/s13059-014-0413-3.pdf

Reference58 articles.

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2. Huminiecki L, Wolfe KH: Divergence of spatial gene expression profiles following species-specific gene duplications in human and mouse. Genome Res. 2004, 14: 1870-1879. 10.1101/gr.2705204.

3. Struhl K: Fundamentally different logic of gene regulation in eukaryotes and prokaryotes. Cell. 1999, 98: 1-4. 10.1016/S0092-8674(00)80599-1.

4. Ptashne MGA: Genes and signals. 2002, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York

5. Segal E, Raveh-Sadka T, Schroeder M, Unnerstall U, Gaul U: Predicting expression patterns from regulatory sequence in Drosophila segmentation. Nature. 2008, 451: 535-U531. 10.1038/nature06496.

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