Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis
Author:
Funder
Bayer HealthCare
Publisher
Springer Science and Business Media LLC
Subject
Critical Care and Intensive Care Medicine
Link
http://link.springer.com/content/pdf/10.1186/s13054-017-1636-y.pdf
Reference36 articles.
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2. Kumar G, Kumar N, Taneja A, Kaleekal T, Tarima S, McGinley E, et al. Milwaukee Initiative in Critical Care Outcomes Research Group of Investigators. Nationwide trends of severe sepsis in the 21st century (2000–2007). Chest. 2011;140:1223–31.
3. Esmon CT. The interactions between inflammation and coagulation. Br J Haematol. 2005;131:417–30.
4. Angus DC, van der Poll T. Severe sepsis and septic shock. New Engl J Med. 2013;29(369):840–51.
5. Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med. 2010;38(2 Suppl):S26–34.
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