Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine

Author:

Advani Gahana,Lim Ya Chee,Catimel Bruno,Lio Daisy Sio Seng,Ng Nadia L. Y.,Chüeh Anderly C.,Tran Mai,Anasir Mohd Ishtiaq,Verkade Heather,Zhu Hong-Jian,Turk Benjamin E.,Smithgall Thomas E.,Ang Ching-Seng,Griffin Michael,Cheng Heung-Chin

Funder

National Health and Medical Research Council

National Institutes of Health

Australian Research Council

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference84 articles.

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2. Cordero JB, Ridgway RA, Valeri N, Nixon C, Frame MC, Muller WJ, Vidal M, Sansom OJ. C-Src drives intestinal regeneration and transformation. EMBO J. 2014;33:1474–91.

3. Lehrer S, O'Shaughnessy J, Song HK, Levine E, Savoretti P, Dalton J, Lipsztein R, Kalnicki S, Bloomer WD. Activity of pp60c-src protein kinase in human breast cancer. Mt Sinai J Med. 1989;56:83–5.

4. Irby RB, Yeatman TJ. Role of Src expression and activation in human cancer. Oncogene. 2000;19:5636–42.

5. Stettner MR, Wang W, Nabors LB, Bharara S, Flynn DC, Grammer JR, Gillespie GY, Gladson CL. Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Res. 2005;65:5535–43.

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