The design of high affinity human PD-1 mutants by using molecular dynamics simulations (MD)
Author:
Funder
Jiangfeng Du
Wenshan Zhao
Yanfeng Gao
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://link.springer.com/content/pdf/10.1186/s12964-018-0239-9.pdf
Reference38 articles.
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3. Shinohara T, et al. Structure and chromosomal localization of the human PD-1 gene (PDCD1). Genomics. 1994;23(3):704–6.
4. Karwacz K, et al. PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells. EMBO Mol Med. 2011;3(10):581–92.
5. Shi L, et al. The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies. J Hematol Oncol. 2013;6(1):74.
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