Abstract
Abstract
Background
Hemophilia B is an X-linked inherited disease, mainly caused by deficiency of factor IX. Severity of the disease is manifested by the factor IX deficiency in the blood.
Case presentation
This paper presents our experience in the cochlear implantation with hemophilia B in an 11-month child with profound sensorineural hearing loss. The patient had normal hematological parameters pre-operatively and surgery was uneventful. After 36 h of the surgery, the patient developed right periorbital ecchymosis, extending to the left eye with a soakage of bandage. With timely early intervention, the bleeding stopped and ecchymosis was resolved.
Conclusion
To our knowledge, cochlear implantation in hemophilia B has not been reported previously. Cochlear implantation can be safely done in hemophilia A and B with timely correction of deficient factors.
Publisher
Springer Science and Business Media LLC
Subject
Otorhinolaryngology,General Medicine
Reference10 articles.
1. Cancio MI, Reiss UM, Nathwani AC, Davidoff AM, Gray JT (2013) Developments in the treatment of hemophilia B: focus on emerging gene therapy. Appl Clin Genet 6:91–101
2. Franchini M (2014) Current management of hemophilia B: recommendations, complications and emerging issues. Expert Rev Hematol 7(5):573–581
3. Mannucci PM, Tuddenham EG (2001) The hemophilias-from royal genes to gene therapy. N Engl J Med 344(23):1773–1779
4. Dolan G, Benson G, Duffy A, Hermans C, Jiménez-Yuste V et al (2018) Haemophilia B: Where are we now and what does the future hold? Blood Rev 32(1):52–60
5. Biggs R, Douglas A, Macfarlane RG, Dacie JV, Pitney WR, Merskey C et al (1952) Christmas disease; a condition previously mistaken for hemophilia. Brit MJ 2:1378–1382
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