Correlation between the perineural invasion and neck metastasis in patients with laryngeal carcinoma: a cross sectional study

Abstract

Abstract Background One of the most problematic issues of laryngeal carcinoma is recurrence after surgery one of the causes of recurrence this study tries to find its relevance is the peri neural invasion. Aim of the work To determine whether there is a relationship between perineural invasion and cervical nodal metastases of laryngeal squamous cell carcinoma. Methods Between December 2019 and September 2020, this study was conducted on 30 individuals who had laryngeal SCC. After the surgical removal of the tumor, a histological examination was done to check for the existence of perineural invasion, which was later linked to the cervical nodal metastases. Results Of our patients 26.7% (8/30) had perineural invasion. Perineural invasion and cervical nodal metastasis were statistically significantly associated (P value = 0.018). Conclusion A strong histologic predictor of cervical nodal metastases is perineural invasion.