Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent

Author:

El-Kalyoubi Samar A.

Publisher

Springer Science and Business Media LLC

Subject

General Chemistry

Reference42 articles.

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2. Ruanpanun P, Laatsch H, Tangchitsomkid N, Lumyong S (2011) Nematicidal activity of fervenulin isolated from a nematicidal actinomycete, Streptomyces sp. CMU-MH021, on Meloidogyne incognita. World J Microbiol Biotechnol 27:1373–1380

3. Nagamatsu T, Yamasaki H, Hirota T, Yamato M, Kido Y, Shibata M, Yoneda F (1993) Syntheses of 3-substituted 1-methyl-6-phenylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-diones (6-phenyl analogs of toxoflavin) and their 4-oxides, and evaluation of antimicrobial activity of toxoflavins and their analogs. Chem Pharm Bull 41:362–368

4. Kiselev OI, Deyeva EG, Melnicova TI, Kozeletskaia KN, Kiselev AS, Rusinov VL, Charushin VN, Chupahin ON (2012) A new antiviral drug triazavirin: results of phase II clinical trial. Vopr Virusol 57:9–12

5. Abdel-Rahman RM, Seada M, Fawzy M, El-Baz I (1994) Synthesis of some new 1,6-dihydro-3-substituted 6-spiro-(9′-fluorene)-1,2,4-triazin-5-(4H)-ones as potential anti HIV and anticancer drugs. Pharmazie 49:729–733

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