Regioselective semi-synthesis of 6-isomers of 5,8-O-dimethyl ether of shikonin derivatives via an ‘intramolecular ring-closing/ring-opening’ strategy as potent anticancer agents-Reference-Cited by-同舟云学术

Regioselective semi-synthesis of 6-isomers of 5,8-O-dimethyl ether of shikonin derivatives via an ‘intramolecular ring-closing/ring-opening’ strategy as potent anticancer agents

Published:2017-08-02 Issue:1 Volume:11 Page:
ISSN:1752-153X
Container-title:Chemistry Central Journal
language:en
Short-container-title:Chemistry Central Journal

Author:

Zhou Li,Zhang Xu,Zhou Wen^ORCID

Funder

Startup foundation of Guangzhou University of Chinese Medicine

Guangzhou University of Chinese Medicine

Publisher

Springer Science and Business Media LLC

Subject

General Chemistry

Link

http://link.springer.com/content/pdf/10.1186/s13065-017-0306-0.pdf

Reference27 articles.

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3. Papageorgiou VP, Assimopoulou AN, Samanidu VF (2006) Recent advances in chemistry, biology and biotechnology of alkannins and shikonins. Cur Org Chem 10(16):2123–2142

4. Song GY, Zheng XG, Kim Y, You YJ, Sok DE, Ahn BZ (1999) Naphthazarin derivatives (II): formation of glutathione conjugate, inhibition of DNA topoisomerase-l and cytotoxicity. Bioorg Med Chem Lett 9(16):2407–2412

5. Song GY, Kim Y, Zheng XG, You YJ, Cho H, Chung JH, Sok DE, Ahn BZ (2000) Naphthazarin derivatives (IV): synthesis, inhibition of DNA topoisomerase-l and cytotoxicity of 2-or 6-acyl-5,8-dimethoxy-1,4-naphthoquinones. Eur J Med Chem 31(31):291–298

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