Novel mutations in the VKORC1 gene of wild rats and mice – a response to 50 years of selection pressure by warfarin?-Reference-Cited by-同舟云学术

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Novel mutations in the VKORC1 gene of wild rats and mice – a response to 50 years of selection pressure by warfarin?

Published:2009-02-06 Issue:1 Volume:10 Page:
ISSN:1471-2156
Container-title:BMC Genetics
language:en
Short-container-title:BMC Genet

Author:

Rost Simone,Pelz Hans-Joachim,Menzel Sandra,MacNicoll Alan D,León Vanina,Song Ki-Joon,Jäkel Thomas,Oldenburg Johannes,Müller Clemens R

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics

Link

http://link.springer.com/content/pdf/10.1186/1471-2156-10-4.pdf

Reference30 articles.

1. Bell RG, Caldwell PT: Mechanism of warfarin resistance. Warfarin and the metabolism of vitamin K 1. Biochemistry. 1973, 12: 1759-62. 10.1021/bi00733a015.

2. Zimmermann A, Matschiner JT: Biochemical basis of hereditary resistance to warfarin in the rat. Biochem Pharmacol. 1974, 23: 1033-40. 10.1016/0006-2952(74)90002-1.

3. Rost S, Fregin A, Ivaskevicius V, Conzelmann E, Hortnagel K, Pelz HJ, Lappegard K, Seifried E, Scharrer I, Tuddenham EG, Muller CR, Strom TM, Oldenburg J: Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature. 2004, 427: 537-541. 10.1038/nature02214.

4. Li T, Chang CY, Jin DY, Lin PJ, Khvorova A, Stafford DW: Identification of the gene for vitamin K epoxide reductase. Nature. 2004, 427: 541-544. 10.1038/nature02254.

5. Sadowski JA, Esmon CT, Suttie JW: Vitamin K-dependent carboxylase. Requirements of the rat liver microsomal enzyme system. J Biol Chem. 1976, 251: 2770-6.

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