Progress on the roles of MEF2C in neuropsychiatric diseases-Reference-Cited by-同舟云学术

Progress on the roles of MEF2C in neuropsychiatric diseases

Published:2022-01-06 Issue:1 Volume:15 Page:
ISSN:1756-6606
Container-title:Molecular Brain
language:en
Short-container-title:Mol Brain

Author:

Zhang Zhikun,Zhao Yongxiang^ORCID

Abstract

AbstractMyocyte Enhancer Factor 2 C (MEF2C), one of the transcription factors of the MADS-BOX family, is involved in embryonic brain development, neuronal formation and differentiation, as well as in the growth and pruning of axons and dendrites. MEF2C is also involved in the development of various neuropsychiatric disorders, such as autism spectrum disorders (ASD), epilepsy, schizophrenia and Alzheimer’s disease (AD). Here, we review the relationship between MEF2C and neuropsychiatric disorders, and provide further insights into the mechanism of these diseases.

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Link

https://link.springer.com/content/pdf/10.1186/s13041-021-00892-6.pdf

Reference86 articles.

1. Adachi M, Lin PY, Pranav H, Monteggia LM. Postnatal loss of Mef2c results in dissociation of effects on synapse number and learning and memory. Biol Psychiatry. 2016;80(2):140–8. https://doi.org/10.1016/j.biopsych.2015.09.018.

2. Akhtar MW, Kim MS, Adachi M, Morris MJ, Qi X, Richardson JA, et al. In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival. PLoS ONE. 2012;7(4):e34863. https://doi.org/10.1371/journal.pone.0034863.

3. Angelelli C, Magli A, Ferrari D, Ganassi M, Matafora V, Parise F, et al. Differentiation-dependent lysine 4 acetylation enhances MEF2C binding to DNA in skeletal muscle cells. Nucleic Acids Res. 2008;36(3):915–28. https://doi.org/10.1093/nar/gkm1114.

4. Assali A, Harrington AJ, Cowan CW. Emerging roles for MEF2 in brain development and mental disorders. Curr Opin Neurobiol. 2019;59:49–58. https://doi.org/10.1016/j.conb.2019.04.008.

5. Bai XL, Zhang Q, Ye LY, Liang F, Sun X, Chen Y, et al. Myocyte enhancer factor 2C regulation of hepatocellular carcinoma via vascular endothelial growth factor and Wnt/beta-catenin signaling. Oncogene. 2015;34(31):4089–97. https://doi.org/10.1038/onc.2014.337.

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