Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression-Reference-Cited by-同舟云学术

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Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

Published:2015-09-18 Issue:1 Volume:8 Page:
ISSN:1756-6606
Container-title:Molecular Brain
language:en
Short-container-title:Mol Brain

Author:

Ho Dong Hwan,Kim Hyejung,Kim Jisun,Sim Hyuna,Ahn Hyunjun,Kim Janghwan,Seo Hyemyung,Chung Kwang Chul,Park Bum-Joon,Son Ilhong,Seol Wongi

Funder

the National Research Foundation of Korea

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Link

http://link.springer.com/content/pdf/10.1186/s13041-015-0145-7.pdf

Reference80 articles.

1. Martin I, Dawson VL, Dawson TM. Recent advances in the genetics of Parkinson's disease. Annu Rev Genomics Hum Genet. 2011;12:301–25.

2. Seol W. Biochemical and molecular features of LRRK2 and its pathophysiological roles in Parkinson's disease. BMB Rep. 2010;43:233–44.

3. Paisan-Ruiz C, Jain S, Evans EW, Gilks WP, Simon J, van der Brug M, et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron. 2004;44:595–600.

4. Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, Lincoln S, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron. 2004;44:601–7.

5. Gilsbach BK, Kortholt A. Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation. Front Mol Neurosci. 2014;7:32.

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