Estrogen receptor transcription and transactivation Estrogen receptor knockout mice: what their phenotypes reveal about mechanisms of estrogen action
Author:
Publisher
Springer Science and Business Media LLC
Link
http://link.springer.com/content/pdf/10.1186/bcr79.pdf
Reference43 articles.
1. Eddy EM, Washburn TF, Bunch DO, Goulding EH, Gladen BC, Lubahn DB, Korach KS: Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology. 1996, 137: 4796-4805. 10.1210/en.137.11.4796., This study describes the phenotype seen in the aERKO males, which was unexpected because a role for estrogen in male reproduction was not predicted.
2. Hess RA, Bunick D, Lee KH, Bahr J, Taylor JA, Korach KS, Lubahn DB: A role for oestrogens in the male reproductive system. Nature. 1997, 390: 509-512. 10.1038/37352., This study describes the mechanism leading to infertility in the aERKO male — the luminal fluid is not reabsorbed, further defining the role of estrogen in male reproduction
3. Mahato D, Goulding EH, Korach KS, Eddy EM: Spermatogenic cells do not require estrogen receptor alpha for development or function. Endocrinology. 2000, 141: 1273-1276. 10.1210/en.141.3.1273., A sophisticated study in which aERKO germ cells are grown in the testis of a normal donor, resulting in fertile sperm. This indicates that the role of estrogen is not in production of fertile sperm per se, but in providing the proper structures and processes for maturation to occur successfully
4. Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O: Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA. 1993, 90: 11162-11166., This is the first report of the generation of aERKO mice and presents a basic description of the phenotypes
5. Couse JF, Korach KS: Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev. 1999, 20: 358-417. 10.1210/er.20.3.358.
Cited by 116 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Rodent models in polycystic ovarian syndrome: Dissecting reproductive and metabolic phenotypes for therapeutic advancements;Steroids;2024-11
2. Murine uterine gland branching is necessary for gland function in implantation;Molecular Human Reproduction;2024-05-24
3. The impact of estradiol on serotonin, glutamate, and dopamine systems;Frontiers in Neuroscience;2024-03-22
4. Ovaries of estrogen receptor 1-deficient mice show iron overload and signs of aging;Frontiers in Endocrinology;2024-02-23
5. Chronology of Anticancer Drugs and Their Development;Handbook of Oncobiology: From Basic to Clinical Sciences;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3