Negative 18F-FET PET/CT in brain metastasis recurrence: a teaching case report-Reference-Cited by-同舟云学术

Negative 18F-FET PET/CT in brain metastasis recurrence: a teaching case report

Published:2021-11-22 Issue:1 Volume:5 Page:
ISSN:2510-3636
Container-title:European Journal of Hybrid Imaging
language:en
Short-container-title:European J Hybrid Imaging

Author:

Alshehri Samirah^ORCID,Prior John,Moshebah Mohammed,Schiappacasse Luis,Dunet Vincent

Abstract

AbstractPositron emission tomography (PET) using O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET has been shown to be a useful tool for differentiating radiation therapy outcomes, such as brain metastasis recurrence or radiation necrosis. We present the case of a female patient with brain metastases from pulmonary mucinous adenocarcinoma with suspicion of tumor recurrence on follow-up magnetic resonance imaging (MRI) after radiosurgery. 18F-FET PET/computed tomography (CT) was indicative of radiation necrosis. Due to the patient's medical history and the discrepancy between the brain MRI and PET/CT results, surgical biopsies were decided, which were positive for brain metastasis recurrence. The diagnosis of metastasis recurrence may also be challenging on 18F-FET PET/CT. In case of discrepancies between MRI and PET/CT results, false-negative 18F-FET PET/CT remains a possibility and requires careful follow-up or biopsy.

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging,Molecular Medicine,Biophysics,Computer Science (miscellaneous)

Link

https://link.springer.com/content/pdf/10.1186/s41824-021-00115-0.pdf

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