A study on prevalence of rotavirus infection in children below 5 years, with acute gastroenteritis

Author:

Manick Dass S.,Pattnaik Snigdha,Amulya K.

Abstract

Background: Diarrheal diseases are among the most frequent causes of morbidity and mortality in children worldwide, especially in India. This cross sectional study was conducted to investigate the causative agent of diarrhea among children, below five years, treated at an urban tertiary care hospital, Telangana.Methods: Stool specimens were collected from 240 children under 5 years of age visiting Apollo Medical College, General Hospital in Hyderabad, hospitals due to acute diarrhea. Rapid stool antigen immunochromatograhic testing was used to diagnose rota virus diarrhea. In this test the VP 6 antigen present on the middle layer of the virus capsule is detected.Results: During the 2 months of the study period, 60 children visited the institute seeking treatment of diarrhoea. 11 (18%) of, the children were found to be positive for rota virus infection. It was also observed that, due to advent of rotavirus vaccine, incidence of diarrhea has come down.Conclusions: In our study the prevalence of rotavirus infection in children suffering from acute gastroenteritis below five years of age is 18.3%. This study is performed using an ICT rapid card test in which group A of the rotavirus is detected, the drawback of this study is other groups of rotavirus like B and C which also cause human infections are not detected. Following the rapid ICT card test which is a diagnostic test, ELISA, confirmatory test for the detection of rotavirus should also be done.

Publisher

Medip Academy

Subject

General Medicine

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Epidemiology of rotavirus infection: the evolution of the pathogen and the success of vaccination;Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics);2024-05-08

2. Assessment of Rotavirus Infection in Hospitalized Children with Diarrhea;Archives of Pediatric Infectious Diseases;2023-01-28

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