Author:
Silky Silky,Singh Vishwambhar,Kumar Rajesh,Chaudhary Ashvanee Kumar,Yadav Shishupal,Gupta Deepak Kumar,Goyal Arpit,Yadav Ram Raj,Rahul Rahul,Panday Akshat
Abstract
<p class="abstract">Rosai Dorfman disease is characterised by sinus histiocytosis with massive lymphadenopathy. Here, we present a case report of 33-year female with low grade fever and multiple swellings of variable size in cervical region. Laboratory examinations showed erythrocyte sedimentation rate to be increased up to 40 mm / hour. Histopathological examination revealed a number of histiocytes containing lymphocytes and few plasma cells in their cytoplasm showing emperipolesis of plasma cells and lymphocytes. Immunohistochemistry showed positivity for CD68 with marked sinus expansion by histiocytic cells and emperipolesis. Treatment with tapering dose of systemic corticosteroids over 1 month gave excellent results.</p>
Cited by
1 articles.
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1. Rosai Dorfman Disease: A Rare Case Report;Indian Journal of Otolaryngology and Head & Neck Surgery;2023-12-11