Breaking barriers in HIV treatment: the game-changing impact of lenacapavir

Author:

Mukhtar Sameen,Haris Muhammad

Abstract

HIV is a lentivirus that selectively targets and infects CD4 cells, which are integral to the immune system. Through viral integration and replication, infected cells are gradually destroyed, leading to a weakened immune system and an increased susceptibility to illnesses. The HIV epidemic has resulted in approximately 40.1 million deaths and 84.2 million infections to date, with 38.4 million individuals living with HIV as of the end of 2021. The estimated global prevalence of HIV in adults aged 15 to 49 is 0.7%.

Publisher

Medip Academy

Subject

General Medicine

Reference6 articles.

1. WebMD. How to Treat HIV, 2023. Available at: https://www.webmd.com/hivaids/understandingaids-hiv-treatment#091e9c5e80008962-1-3. Accessed on 01 October 2023.

2. Sunlenca. SUNLENCA® Was Granted FDA Breakthrough Therapy Designation and Has a Novel MOA1,2, 2023. Available at: https://www. sunlencahcp.com/howsunlencaworks/first-in-class-moa/. Accessed on 01 October 2023.

3. Dvory-Sobol H, Shaik N, Callebaut C, Rhee MS. Lenacapavir: a first-in-class HIV-1 capsid inhibitor. Curr Opin HIV AIDS. 2022;17(1):15-21.

4. Maurer S, DeJesus E, Stellbrink HJ, Castagna A, Richmond GJ, Sinclair GI, Siripassorn K, Ruane PJ, Berhe M, Wang H, Margot NA, Dvory-Sobol H, Hyland RH, Brainard DM, Rhee MS, Baeten JM, Molina JM; CAPELLA Study Investigatoet alrs. Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection. N Engl J Med. 2022;386(19):1793-803.

5. REUTERS. U.S. FDA approves Gilead's long-acting HIV drug Sunlenca, 2023. Available at: https://www.reuters.com/business/healthcarlongacting-hiv-drug-sunlenca-2022-12-22/. Accessed on 01 October 2023.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3