Think beyond the Skin

Author:

Gulliver Wayne12345,Lynde Charles12345,Dutz Jan P.12345,Vender Ronald B.12345,Yeung Jensen12345,Bourcier Marc12345,Dion Pierre-Luc12345,Hong Chi-Ho12345,Searles Gordon12345,Poulin Yves12345

Affiliation:

1. Faculty of Medicine, Division of Dermatology, Memorial University, St. John’s NL

2. Department of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ON

3. Department of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC

4. Department of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph’s Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ON

5. Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON

Abstract

Objective: Explore the feasibility of Treat to Target in the area of psoriasis as seen in other therapeutic areas such as hypertension, hyperlipidemia, diabetes and rheumatoid arthritis. Methods: Review validated, measurable targets for psoriasis, including physician global assessment (PGA), psoriasis area and severity index (PASI) and dermatology life quality index (DLQI). Examine principles brought forth in the published European consensus on psoriasis and develop a Canadian consensus on Treat to Target in psoriasis. Results: As PASI and DLQI are not routinely used in the community setting, we are recommending target at a PGA of zero (clear). Conclusion: Recommend that the target is a PGA of zero (clear) as it provides a simple and measurable result that the patient and physician can clearly understand.

Publisher

SAGE Publications

Subject

Dermatology,Surgery

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