EVALUATE CLINICAL EFFICACY OF BIOCERAMIC TECHNOLOGY ON PSYCHOPATHICALLY RELATED SPASMODIC TORTICOLLIS USING MOTION MEASUREMENTS, COMPUTERIZED ANALYSIS OF FACIAL EMOTIONS AND SPEECH SIGNAL FEATURES

Author:

Leung Ting Kai123ORCID,Yang Tzu-Sen4,Lin Ray F.5,Tsai Du Ming5,Chou Chin Mei5

Affiliation:

1. Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan District, Taoyuan City 330, Taiwan

2. Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan

3. College of Health Care and Management, Kainan University, 33857, No.1, Kainan Rd., Luzhu, Taoyuan, Taiwan

4. Graduate Institute of Biomedical Optomchatronics, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan

5. Department of Industrial Engineering and Management, Yuan-Ze University, 135 Yuan-Tung Road, Nei-Li, Tao-Yuan 32026, Taiwan

Abstract

Objective: Spasmodic torticollis is a debilitating neurological movement disorder associated with somatization, obsessive-compulsive, interpersonal sensitivity, depression, and anxiety. Usually, clinician had difficulty to precisely and quantitatively describe clinical outcomes using measurements of patients’ facial and neck movements. Methods: Motion speed changes and direction complexity, computerized facial emotion and assessment, measurement of speech signal features are the quantitative measurements of patients’ head motions, facial expressions, and speech signal features analysis were used to assess clinical effects of bioceramic resonance and photoluminescence of bioceramics (BR&PLB) treatment of psychopathically related spasmodic torticollis. Results: After BR&PLB treatment, there were significant improvements in involuntary movements of patients with spasmodic torticollis measured by motion speed changes and direction complexity (MSCDC). Furthermore, a computerized facial emotion assessment (CFEA) showed that patients expressed greater positive emotions after treatment. Finally, we also performed quantitative assessments on voice analysis of speech signal features (SSF). Conclusions: Our study had achieved three major factors: (i) the clinical efficacy of BR&PLB on psychopathically related spasmodic torticollis; (ii) motion manifestations of spasmodic torticollis in “speed” and “direction” of muscular movements as assessed using “motion measurements” of a computer vision system; and (iii) psychological and emotional factors being directly correlated with the severity of spasmodic torticollis which improved after BR&PLB, and could be qualitatively assessed using FaceReader. This study encourages further investigations of the clinical efficacy of Bioceramic technology on psychopathically related repetitive behavior disorders, and demonstrates effectiveness of MSCDC, CFEA and SSF in providing quantitative assessments of emotion.

Funder

Health Promotion Administration, Ministry of Health and Welfare

Publisher

National Taiwan University

Subject

Biomedical Engineering,Bioengineering,Biophysics

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