CLASSIFICATION OF SCHIZOPHRENIA USING SVM VIA fNIRS

Author:

Dadgostar Mehrdad1,Setarehdan Seyed Kamaledin2,Shahzadi Sohrab3,Akin Ata4

Affiliation:

1. Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

2. Control and Intelligent Processing Center of Excellence, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran

3. Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Center of Excellence, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Department of Medical Engineering, Acibadem University, Istanbul, Turkey

Abstract

In the present study, a classification of functional near-infrared spectroscopy (fNIRS) based on support vector machine (SVM) is presented. It is a non-invasive method monitoring human brain function by evaluating the concentration variation of oxy-hemoglobin and deoxy-hemoglobin. fNIRS is a functional optical imaging technology that measures the neural activities and hemodynamic responses in brain. The data were gathered from 11 healthy volunteers and 16 schizophrenia of the same average age by a 16-channel fNIRS (NIROXCOPE 301 system developed at the Neuro-Optical Imaging Laboratory, continuous-wave dual wavelength). Schizophrenia is a mental disorder that is characterized by mental processing collapse and weak emotional responses. This mental disorder is usually accompanied by a serious disturbance in social and occupational activities. The signals were initially preprocessed by DWT to remove any systemic physiological impediment. A preliminary examination by the genetic algorithm (GA) suggested that some channels of the recreated fNIRS signals required further investigation. The energy of these recreated channel signals was computed and utilized for signal arrangement. We used SVM-based classifier to determine the cases of schizophrenia. The result of six channels is higher than 16 channels. The results demonstrated a classification precision of about 87% in the discovery of schizophrenia in the healthy subjects.

Publisher

National Taiwan University

Subject

Biomedical Engineering,Bioengineering,Biophysics

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