Aloe Vera Bitkisinden Yeşil Sentez Yöntemiyle Elde Edilen Gümüş Nanopartiküllerin Antimikrobiyal ve Antibiyofilm Etkilerinin Araştırılması

Abstract

Misuse of antibiotics globally has resulted in the development of resistant bacterial strains. Antimicrobial and antibiofilm effects of silver nanoparticles obtained by green synthesis from Aloe vera extract against Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus were investigated. The synthesis of silver nanoparticles from the aloe vera plant was carried out by the green synthesis method. After the characterization of silver nanoparticles was evaluated by UV-Vis Spectroscopy, FT-IR, SEM, TEM, XRD its antimicrobial effect on pathogenic microorganisms was evaluated by microdilution method. The Minimum Inhibitor Concentration (MIC) values (µg/mL) of silver nanoparticles on Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus were found to be 32, 64, 32 and 32, respectively. In this study, the biofilm inhibition rate was evaluated by the crystal violet method. Green synthesis silver nanoparticles showed antibiofilm effect on bacteria.