Diagnostic Challenges of Old Diseases in the COVID-19 Era: A Report of Two Cases of Carbamazepine-Induced DRESS Syndrome
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Published:2022
Issue:10
Volume:34
Page:e101-e103
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ISSN:1044-7946
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Container-title:Wounds: a compendium of clinical research and practice
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language:
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Short-container-title:Wounds
Author:
Yakut Nurhayat,Yuksel Emrullah,Algul Mahmut,Armut Mustafa,Akar Himmet
Abstract
Introduction. A new MIS-C that develops after the acute stage of COVID-19 infection has recently been reported worldwide. Drug reaction with eosinophilia and systemic symptoms syndrome is a rare but potentially severe adverse drug-induced reaction most commonly associated with anticonvulsants. Due to variability in clinical presentation involving cutaneous and multiorgan systems, broad differential diagnosis, and lack of definitive diagnostic tests, diagnosis may be delayed. Case Reports. The authors report 2 cases of pediatric patients who presented with fever, diffuse rash, and exposure to COVID-19 infection with suspected MIS-C. Both patients’ medical histories revealed carbamazepine treatment for approximately 2 months. The diagnosis of DRESS syndrome was associated with the use of carbamazepine. Conclusions. Distinguishing between MIS-C and DRESS syndrome may be difficult due to similar clinical and laboratory features and the lack of definitive diagnostic tests for either condition. When encountering cases like the current report, it is important to consider DRESS syndrome for early diagnosis and medical intervention.
Publisher
HMP Communications, LLC
Subject
Medical–Surgical Nursing,Surgery
Cited by
2 articles.
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1. Carbamazepine;Reactions Weekly;2023-01-07
2. Side effects of antiseizure medications;Side Effects of Drugs Annual;2023