Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells
Author:
Affiliation:
1. Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba
2. Faculty of Pharmaceutical Sciences, Tokushima Bunri University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/35/3/35_3_419/_pdf
Reference20 articles.
1. Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene
2. Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts
3. Bashir, S., Sharma, Y., Irshad, M., Nag, T.C., Tiwari, M., Kabra, M. and Dogra, T.D. (2006): Arsenic induced apoptosis in rat liver following repeated 60 days exposure. Toxicology, 217, 63-70.
4. Heme Oxygenase-1: Redox Regulation and Role in the Hepatic Response to Oxidative Stress
5. Guha Mazumder, D.N. (2001): Arsenic and liver disease. J. Indian Med. Assoc., 99, 311, 314-315, 318-320.
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