Toxic effect onset and evaluations of medicinal drugs - horizon for Darwinian toxicological thought -
Author:
Affiliation:
1. Showa University (Department of Biochemical Toxicology, School of Pharmaceutical Sciences)
2. Pfizer (Global Research & Development, Drug Safety Research & Development)
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/35/4/35_4_425/_pdf
Reference44 articles.
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2. Bickham, J.W. and Smolen, M.J. (1994): Somatic and heritable effects of environmental genotoxins and the emergence of evolutionary toxicology. Environ. Health Perspect., 102, 25-28.
3. Signaling pathways and effector mechanisms pre-programmed cell death
4. Mechanisms of caspase activation
5. Specific Targets of Covalent Drug-Protein Interactions in Hepatocytes and Their Toxicological Significance in Drug-Induced Liver Injury
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