Sex differences in the excretion levels of traditional and novel urinary biomarkers of nephrotoxicity in rats

Author:

Tsuji Satoshi1,Sugiura Masayuki1,Tsutsumi Shunsuke1,Yamada Hisaharu1

Affiliation:

1. Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd.

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference36 articles.

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2. Birn, H., Fyfe, J.C., Jacobsen, C., Mounier, F., Verroust, P.J., Orskov, H., Willnow, T.E., Moestrup, S.K. and Christensen, E.I. (2000): Cubilin is an albumin binding protein important for renal tubular albumin reabsorption. J. Clin. Invest., 105, 1353-1361.

3. Bonventre, J.V., Vaidya, V.S., Schmouder, R., Feig, P. and Dieterle, F. (2010): Next-generation biomarkers for detecting kidney toxicity. Nat. Biotechnol., 28, 436-440.

4. Cui, S., Verroust, P.J., Moestrup, S.K. and Christensen, E.I. (1996): Megalin/gp330 mediates uptake of albumin in renal proximal tubule. Am. J. Physiol., 271, F900-F907.

5. Dieterle, F., Sistare, F., Goodsaid, F., Papaluca, M., Ozer, J.S., Webb, C.P., Baer, W., Senagore, A., Schipper, M.J., Vonderscher, J., Sultana, S., Gerhold, D.L., Phillips, J.A., Maurer, G., Carl, K., Laurie, D., Harpur, E., Sonee, M., Ennulat, D., Holder, D., Andrews-Cleavenger, D., Gu, Y.Z., Thompson, K.L., Goering, P.L., Vidal, J.M., Abadie, E., Maciulaitis, R., Jacobson-Kram, D., Defelice, A.F., Hausner, E.A., Blank, M., Thompson, A., Harlow, P., Throckmorton, D., Xiao, S., Xu, N., Taylor, W., Vamvakas, S., Flamion, B., Lima, B.S., Kasper, P., Pasanen, M., Prasad, K., Troth, S., Bounous, D., Robinson-Gravatt, D., Betton, G., Davis, M.A., Akunda, J., McDuffie, J.E., Suter, L., Obert, L., Guffroy, M., Pinches, M., Jayadev, S., Blomme, E.A., Beushausen, S.A., Barlow, V.G., Collins, N., Waring, J., Honor, D., Snook, S., Lee, J., Rossi, P., Walker, E., and Mattes, W. (2010): Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium. Nat. Biotechnol., 28, 455-462.

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