The effects on the endocrine system under hepatotoxicity induction by phenobarbital and di(2-ethylhexyl)phthalate in intact juvenile male rats
Author:
Affiliation:
1. Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd.
2. Laboratory of Animal Reproductive Physiology, Graduate School of Environmental and Life Science, Okayama University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/44/7/44_459/_pdf
Reference47 articles.
1. Akingbemi, B.T., Ge, R., Klinefelter, G.R., Zirkin, B.R. and Hardy, M.P. (2004): Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances. Proc. Natl. Acad. Sci. USA, 101, 775-780.
2. Akingbemi, B.T., Youker, R.T., Sottas, C.M., Ge, R., Katz, E., Klinefelter, G.R., Zirkin, B.R. and Hardy, M.P. (2001): Modulation of rat Leydig cell steroidogenic function by di(2-ethylhexyl)phthalate. Biol. Reprod., 65, 1252-1259.
3. Barakat, R., Lin, P.P., Rattan, S., Brehm, E., Canisso, I.F., Abosalum, M.E., Flaws, J.A., Hess, R. and Ko, C. (2017): Prenatal Exposure to DEHP Induces Premature Reproductive Senescence in Male Mice. Toxicol. Sci., 156, 96-108.
4. Barter, R.A. and Klaassen, C.D. (1992): Rat liver microsomal UDP-glucuronosyltransferase activity toward thyroxine: characterization, induction, and form specificity. Toxicol. Appl. Pharmacol., 115, 261-267.
5. Cha, S., Jung, K., Lee, M.Y., Hwang, Y.J., Yang, E., Lee, S.H., Jung, H.I. and Cheon, Y.P. (2018): Nonmonotonic effects of chronic low-dose Di(2-ethylhexyl) phthalate on gonadal weight and reproductive. Dev. Reprod., 22, 85-94.
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