Titanium dioxide and silica nanoparticles inhibit the efflux of adriamycin in multi-drug resistant L1210/ADM cells
Author:
Affiliation:
1. School of Pharmacy, Department of Pharmacy, Hyogo Medical University
2. Department of Pharmacy, Otemae Hospital
3. Department of Pharmacology, Chiba University Graduate School of Medicine
Publisher
Japanese Society of Toxicology
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/fts/10/6/10_259/_pdf
Reference17 articles.
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3. Bohácová, V., Sulová, Z., Dovinová, I., Poláková, E., Barancík, M., Uhrík, B., Orlický, J. and Breier, A. (2006): L1210 cells cultivated under the selection pressure of doxorubicin or vincristine express common mechanisms of multidrug resistance based on the overexpression of P-glycoprotein. Toxicol. In Vitro, 20, 1560-1568.
4. Fromm, M.F. (2003): Importance of P-glycoprotein for drug disposition in humans. Eur. J. Clin. Invest., 33 (Suppl 2), 6-9.
5. Fu, P.P., Xia, Q., Hwang, H.M., Ray, P.C. and Yu, H. (2014): Mechanisms of nanotoxicity: generation of reactive oxygen species. Yao Wu Shi Pin Fen Xi, 22, 64-75.
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