Disruption of spindle checkpoint function ahead of facilitation of cell proliferation by repeated administration of hepatocarcinogens in rats
Author:
Affiliation:
1. Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
2. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/40/6/40_855/_pdf
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3. Beutin, L., Preller, E. and Kowalski, B. (1981): Mutagenicity of quindoxin, its metabolites, and two substituted quinoxaline-di-N-oxides. Antimicrob. Agents Chemother., 20, 336-343.
4. Bhattacharya, S. and Ghosh, M.K. (2014): HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator. FEBS J., 281, 3061-3078.
5. Burma, S., Chen, B.P., Murphy, M., Kurimasa, A. and Chen, D.J. (2001): ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem., 276, 42462-42467.
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