The performance of an <i>in vitro</i> skin sensitisation test, IL-8 Luc assay (OECD442E), and the integrated approach with direct peptide reactive assay (DPRA)-Reference-Cited by-同舟云学术

The performance of an in vitro skin sensitisation test, IL-8 Luc assay (OECD442E), and the integrated approach with direct peptide reactive assay (DPRA)

Published:2018 Issue:12 Volume:43 Page:741-749
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Kimura Yutaka¹,Watanabe Mika²,Suzuki Noriyuki³,Iwaki Tomoko⁴,Yamakage Kohji²,Saito Koichi³,Nakajima Yoshihiro⁴,Fujimura Chizu¹,Ohmiya Yoshihiro⁵,Omori Takashi⁶,Kojima Hajime⁷,Aiba Setsuya¹

Affiliation:

1. Department of Dermatology, Tohoku University Graduate School of Medicine

2. Hatano Research Institute, Food and Drug Safety Center

3. Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd.

4. Health Research Institute, Advanced Industrial Science and technology (AIST)

5. Biomedical Research Institute, Advanced Industrial Science and Technology (AIST)

6. Division of Biostatistics, Department of Social/Community Medicine and Health Science, Kobe University School of Medicine

7. Japanese Center for the Validation of Alternative Methods

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/43/12/43_741/_pdf

Reference17 articles.

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2. Gerberick, G.F., Ryan, C.A., Kern, P.S., Schlatter, H., Dearman, R.J., Kimber, I., Patlewicz, G.Y. and Basketter, D.A. (2005): Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis, 16, 157-202.

3. Gerberick, G.F., Vassallo, J.D., Bailey, R.E., Chaney, J.G., Morrall, S.W. and Lepoittevin, J.P. (2004): Development of a peptide reactivity assay for screening contact allergens. Toxicol. Sci., 81, 332-343.

4. Kimura, Y., Fujimura, C., Ito, Y., Takahashi, T., Nakajima, Y., Ohmiya, Y. and Aiba, S. (2015): Optimization of the IL-8 Luc assay as an in vitro test for skin sensitization. Toxicol. In Vitro, 29, 1816-1830.

5. Kimura, Y., Fujimura, C., Ito, Y., Takahashi, T., Terui, H. and Aiba, S. (2018): Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. Arch. Toxicol., 92, 2043-2054.

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