5-Fluorouracil inhibits neural differentiation via Mfn1/2 reduction in human induced pluripotent stem cells
Author:
Affiliation:
1. Division of Pharmacology, National Institute of Health Sciences, Japan
2. Pharmacological Evaluation Institute of Japan (PEIJ), Japan
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/43/12/43_727/_pdf
Reference39 articles.
1. Asanagi, M., Yamada, S., Hirata, N., Itagaki, H., Kotake, Y., Sekino, Y. and Kanda, Y. (2016): Tributyltin induces G2/M cell cycle arrest via NAD(+)-dependent isocitrate dehydrogenase in human embryonic carcinoma cells. J. Toxicol. Sci., 41, 207-215.
2. Chambers, S.M., Fasano, C.A., Papapetrou, E.P., Tomishima, M., Sadelain, M. and Studer, L. (2009): Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol., 27, 275-280.
3. Chan, N.C., Salazar, A.M., Pham, A.H., Sweredoski, M.J., Kolawa, N.J., Graham, R.L., Hess, S. and Chan, D.C. (2011): Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet., 20, 1726-1737.
4. Cheng, A., Hou, Y. and Mattson, M.P. (2010): Mitochondria and neuroplasticity. ASN Neuro, 2, e00045.
5. Chen, H., Detmer, S.A., Ewald, A.J., Griffin, E.E., Fraser, S.E. and Chan, D.C. (2003): Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol., 160, 189-200.
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