Azoxystrobin at sub-cytotoxic concentrations disrupts intracellular zinc homeostasis: A flow cytometric analysis with rat thymic lymphocytes and fluorescent probes
Author:
Affiliation:
1. Graduate School of Integrated Arts and Sciences, Tokushima University
2. Department of Food-Nutritional Sciences, Faculty of Life Sciences, Tokushima Bunri University
Publisher
Japanese Society of Toxicology
Link
https://www.jstage.jst.go.jp/article/fts/7/1/7_1/_pdf
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2. Chikahisa, L., Oyama, Y., Okazaki, E. and Noda, K. (1996): Fluorescent estimation of H2O2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes. Jpn. J. Pharmacol., 71, 299-305.
3. Bortner, C.D. and Cidlowski, J.A. (1998): A necessary role for cell shrinkage in apoptosis. Biochem. Pharmacol., 56, 1549-1559.
4. European Food Safety Authority. (2010): Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin. EFSA J., 8, 1542.
5. Fukada, T., Yamasaki, S., Nishida, K., Murakami, M. and Hirano, T. (2011): Zinc homeostasis and signaling in health and diseases. J. Biol. Inorg. Chem., 16, 1123-1134.
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