Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2’-hydroxy-3’,5’-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences-Reference-Cited by-同舟云学术

Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2’-hydroxy-3’,5’-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences

Published:2016 Issue:5 Volume:41 Page:693-700
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Hirata-Koizumi Mutsuko¹,Ise Ryota²,Kato Hirohito³,Matsuyama Takashi⁴,Nishimaki-Mogami Tomoko⁵,Takahashi Mika¹,Ono Atsushi¹,Ema Makoto⁶,Hirose Akihiko¹

Affiliation:

1. Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences

2. Shin Nippon Biomedical Laboratories, Ltd. (SNBL)

3. Drug Safety Research Laboratories, Shin Nippon Biomedical Laboratories, Ltd. (SNBL)

4. SNBL USA Ltd.

5. Division of Biochemistry and Molecular Biology, National Institute of Health Sciences

6. Research Institute of Science for Safety and Sustainability, National Institute of Advanced Industrial Science and Technology (AIST)

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/41/5/41_693/_pdf

Reference30 articles.

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3. Balasubramaniyan, N., Shahid, M., Suchy, F.J. and Ananthanarayanan, M. (2005): Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development. Am. J. Physiol. Gastrointest Liver Physiol., 288, G251-260.

4. Braissant, O. and Wahli, W. (1998): Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development. Endocrinology, 139, 2748-2754.

5. Desvergne, B. and Wahli, W. (1999): Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev., 20, 649-688.

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