A 90-day repeated oral dose toxicity study of 2-Butylbenzo[d]isothiazol-3(2H)-one in rats
Author:
Affiliation:
1. Division of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Sciences
2. Research Laboratories in Vitro and in Vivo, Higashimatsuyama Laboratories, Drug Safety Testing Center Co., Ltd.
Publisher
Japanese Society of Toxicology
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/fts/10/2/10_69/_pdf
Reference8 articles.
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2. Dietrich, D.R. and Swenberg, J.A. (1991): The presence of alpha 2u-globulin is necessary for d-limonene promotion of male rat kidney tumors. Cancer Res., 51, 3512-3521.
3. Doi, A., Hill, G., Seely, J., Hailey, J.R., Kissling, G. and Bucher, J.R. (2007): α2u-Globulin nephropathy and renal tumors in National Toxicology Program studies. Toxicol. Pathol., 35, 533-540.
4. Greaves, P. (2012): Urinaly Tract, Kidney In Histopathology of Preclinical Toxicity studies, pp. 537-614. London, U.K.: Academic Press.
5. Hamamura, M., Oshikata, T., Katoku, K., Tsuchitani, M. and Yamaguchi, R. (2017): Two types of deposits, hyaline droplets and eosinophilic bodies, associated with α2u-globulin accumulation in the rat kidney. J. Toxicol. Pathol., 30, 275-282.
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