Acyl-CoA:diacylglycerol acyltransferase 1 inhibition in the small intestine increases plasma transaminase activity via the activation of protein kinase C pathway-Reference-Cited by-同舟云学术

Acyl-CoA:diacylglycerol acyltransferase 1 inhibition in the small intestine increases plasma transaminase activity via the activation of protein kinase C pathway

Published:2022 Issue:1 Volume:47 Page:19-30
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Yokoyama Hideaki¹,Masuyama Taku¹,Tanaka Yuki¹,Tsubakihara Iori¹,Kondo Kazuma¹,Yoshinari Kouichi²

Affiliation:

1. Toxicology Research Lab., Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.

2. Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/47/1/47_19/_pdf

Reference32 articles.

1. Bajt, M.L., Lawson, J.A., Vonderfecht, S.L., Gujral, J.S. and Jaeschke, H. (2000): Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8. Toxicol. Sci., 58, 109-117.

2. Blane, G.F. (1987): Comparative toxicity and safety profile of fenofibrate and other fibric acid derivatives. Am. J. Med., 83 (5B), 26-36.

3. Cario, E., Gerken, G. and Podolsky, D.K. (2004): Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C. Gastroenterology, 127, 224-238.

4. Cases, S., Smith, S.J., Zheng, Y.W., Myers, H.M., Lear, S.R., Sande, E., Novak, S., Collins, C., Welch, C.B., Lusis, A.J., Erickson, S.K. and Farese, R.V. Jr. (1998): Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. Proc. Natl. Acad. Sci. USA, 95, 13018-13023.

5. Cases, S., Stone, S.J., Zhou, P., Yen, E., Tow, B., Lardizabal, K.D., Voelker, T. and Farese, R.V. Jr. (2001): Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. J. Biol. Chem., 276, 38870-38876.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Diacylglycerol O-acyltransferase 1 inhibitor increases plasma alanine aminotransferase and aspartate aminotransferase activities via a shedding of the intestinal villi and an increase in intestinal permeability in rats;Toxicology Letters;2024-10