Usefulness of cardiotoxicity assessment using calcium transient in human induced pluripotent stem cell-derived cardiomyocytes
Author:
Affiliation:
1. Preclinical Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/42/4/42_519/_pdf
Reference31 articles.
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2. Chadha, S., Lodha, A., Shetty, V., Sadiq, A., Hollander, G. and Shani, J. (2011): A case of 2:1 atrio - ventricular block in digoxin toxicity. J. Clinic. Experiment. Cardiol., 2, 154.
3. Demiryürek, A.T. and Demiryürek, S. (2005): Cardiotoxicity of digitalis glycosides: roles of autonomic pathways, autacoids and ion channels. Auton. Autacoid. Pharmacol., 25, 35-52.
4. Dempsey, G.T., Chaudhary, K.W., Atwater, N., Nguyen, C., Brown, B.S., McNeish, J.D., Cohen, A.E. and Kralj, J.M. (2016): Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging. J. Pharmacol. Toxicol. Methods, 81, 240-250.
5. Guo, L., Dong, Z. and Guthrie, H. (2009): Validation of a guinea pig Langendorff heart model for assessing potential cardiovascular liability of drug candidates. J. Pharmacol. Toxicol. Methods, 60, 130-151.
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