Central nervous system tumors in 2-year rat carcinogenicity studies: perspectives on human risk assessment
Author:
Affiliation:
1. Pfizer Inc. Drug Safety Research and Development
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/44/10/44_643/_pdf
Reference48 articles.
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2. Bertrand, L., Mukaratirwa, S. and Bradley, A. (2014): Incidence of spontaneous central nervous system tumors in CD-1 mice and Sprague-Dawley, Han-Wistar, and Wistar rats used in carcinogenicity studies. Toxicol. Pathol., 42, 1168-1173.
3. Bjornsti, M.A. and Houghton, P.J. (2004): The TOR pathway: a target for cancer therapy. Nat. Rev. Cancer, 4, 335-348.
4. Bolon, B., Garman, R.H., Pardo, I.D., Jensen, K., Sills, R.C., Roulois, A., Radovsky, A., Bradley, A., Andrews-Jones, L., Butt, M. and Gumprecht, L. (2013): STP position paper: recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies. Toxicol. Pathol., 41, 1028-1048.
5. Boorman, G., Crabbs, T.A., Kolenda-Roberts, H., Latimer, K., Miller, A.D., Muravnick, K.B., Nyska, A., Ochoa, R., Pardo, I.D., Ramot, Y., Rao, D.B., Schuh, J., Suttie, A., Travlos, G.S., Ward, J.M., Wolf, J.C. and Elmore, S.A. (2012): Proceedings of the 2011 National Toxicology Program Satellite Symposium. Toxicol. Pathol., 40, 321-344.
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