Development of QSAR models using artificial neural network analysis for risk assessment of repeated-dose, reproductive, and developmental toxicities of cosmetic ingredients
Author:
Affiliation:
1. Shiseido Research Center, Shiseido Co. Ltd.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/40/2/40_163/_pdf
Reference19 articles.
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2. Cronin, M.T.D. and Worth, A.P. (2008): (Q)SARs for predicting effects relating to reproductive toxicity. QSAR Comb. Sci., 27, 91-100.
3. Hartung, T. and Rovida, C. (2009): Chemical regulators have overreached. Nature, 460, 1080-1081.
4. Hirota, M., Kouzuki, H., Ashikaga, T., Sono, S., Tsujita, K., Sasa, H. and Aiba, S. (2013): Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals. Toxicol. In Vitro, 27, 1233-1246.
5. Jagt, K., Munn, S., Tørsløv, J. and Bruijn, J. (2004): Alternative approaches can reduce the use of test animals under REACH. Report EUR 21405.
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