Children's Immunology, what can we learn from animal studies (2): Modulation of systemic Th1/Th2 immune response in infant mice after prenatal exposure to low-level toluene and tolllike receptor (TLR) 2 ligand

Author:

Yamamoto Shoji1,Shwe Tin-Tin-Win1,Yoshida Yasuhiro2,Kunugita Naoki2,Arashidani Keiichi2,Fujimaki Hidekazu1

Affiliation:

1. National Institute for Environmental Studies

2. University of Occupational and Environmental Health

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference28 articles.

1. Adkins, B., Bu, Y. and Guevara, P. (2001): The generation of Th memory in neonates versus adults: prolonged primary Th2 effector function and impaired development of Th1 memory effector function in murine neonates. J. Immunol., 166, 918-925.

2. Agency for Toxic Substances and Disease Registry (ATSDR). (2000): HEALTH EFFECTS, In: Toxicological profile for toluene, pp. 11-166, Department of Health and Human Services, Public Health Service, Atlanta.

3. Böttcher, M.F., Nordin, E.K., Sandin, A., Midtvedt, T. and Björkstén, B. (2000): Microflora-associated characteristics in faeces from allergic and nonallergic infants. Clin. Exp. Allergy, 30, 1590-1596.

4. Byrne, A., Kirby, B., Zibin, T. and Ensminger, S. (1991): Psychiatric and neurological effects of chronic solvent abuse. Can. J. Psychiatry, 36, 735-738.

5. Curotto de Lafaille M.A. and Lafaille, J.J. (2002): CD4(+) regulatory T cells in autoimmunity and allergy. Curr. Opin. Immunol., 14, 771-778.

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