Collaborative work on evaluation of ovarian toxicity 16) Effects of 2 or 4 weeks repeated dose studies and fertility study of Chlorpromazine hydrochloride in rats

Author:

Izumi Yuko1,Watanabe Takeshi1,Awasaki Naoko1,Hikawa Kenji1,Minagi Takashi1,Chatani Fumio1

Affiliation:

1. Development Research Center, Takeda Pharmaceutical Company Limited

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference16 articles.

1. Barraclough, C.A. (1992): Neural control of the synthesis and release of luteinizing hormone-releasing hormone. Ciba Found. Symp., 168, 233-251.

2. Barraclough, C.A. and Wise, P.M. (1982): The role of catecholamines in the regulation of pituitary luteinizing hormone and follicle-stimulating hormone secretion. Endocr. Rev., 3, 91-119.

3. Baldessarini, R.J. (1985): Drug and the treatment of psychiatric disorders. In Goodman and Gilman's The pharmacological basis of therapeutics. (Gilman, A.G., Goodman, L.S., Rall, T.W. and Murad, F., ed.), pp. 391-447. Macmillan, New York.

4. Bürki, H.R., Ruch, W., Asper, H., Baggiolini, M. and Stille, G. (1974): Effect of single and repeated administration of clozapine on the metabolism of dopamine and noradrenaline in the brain of the rat. Eur. J. Pharmacol., 27, 180-190.

5. Everett, J.W. and Tyrey, L. (1982): Similarity of luteinizing hormone surges induced by medial preoptic stimulation in female rats blocked with pentobarbital, morphine, chlorpromazine, or atropine. Endocrinology, 111, 1979-1985.

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