Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics
Author:
Affiliation:
1. Safety Science Research, Kao Corporation
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/42/4/42_427/_pdf
Reference42 articles.
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2. Björnsson, E. and Olsson, R. (2005): Outcome and prognostic markers in severe drug-induced liver disease. Hepatology, 42, 481-489.
3. Boverhof, D.R. and Zacharewski, T.R. (2006): Toxicogenomics in risk assessment: applications and needs. Toxicol. Sci., 89, 352-360.
4. Chepelev, N.L., Moffat, I.D., Labib, S., Bourdon-Lacombe, J., Kuo, B., Buick, J.K., Lemieux, F., Malik, A.I., Halappanavar, S., Williams, A. and Yauk, C.L. (2015): Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study. Crit. Rev. Toxicol., 45, 44-52.
5. Clewell, H.J., Efremenko, A., Campbell, J.L., Dodd, D.E. and Thomas, R.S. (2014): Transcriptional responses in the rat nasal epithelium following subchronic inhalation of naphthalene vapor. Toxicol. Appl. Pharmacol., 280, 78-85.
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