Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats

Author:

Takami Shigeaki1,Imai Toshio12,Cho Young-Man1,Hirose Masao13,Nishikawa Akiyoshi1

Affiliation:

1. Division of Pathology, National Institute of Health Sciences

2. Central Animal Laboratory, National Cancer Center Research Institute

3. Present address: Food Safety Commission, Cabinet Office

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference34 articles.

1. Assessing Susceptibility from Early-Life Exposure to Carcinogens

2. Carcinogenic activity of acrylamide in the skin and lung of Swiss-ICR mice

3. Burek, J.D., Albee, R.R., Beyer, J.E., Bell, T.J., Carreon, R.M., Morden, D.C., Wade, C.E., Hermann, E.A. and Gorzinski, S.J. (1980): Subchronic toxicity of acrylamide administered to rats in the drinking water followed by up to 144 days of recovery. J. Environ. Pathol. Toxicol., 4, 157-182.

4. Chhabra, R.S., Eustis, S., Haseman, J.K., Kurtz, P.J. and Carlton, B.D. (1992): Comparative carcinogenicity of ethylene thiourea with or without perinatal exposure in rats and mice. Fundam. Appl. Toxicol., 18, 405-417.

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