Induction of CYP3A4 mRNA by cooked food-derived carcinogenic heterocyclic aromatic amines in human HPL-A3 cells
Author:
Affiliation:
1. Laboratory of Environmental Hygiene, Department of Environmental Science, School of Life and Environmental Science, Azabu University
2. Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
Publisher
Japanese Society of Toxicology
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/fts/9/6/9_167/_pdf
Reference25 articles.
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2. Baranczewski, P. and Möller, L. (2004): Relationship between content and activity of cytochrome P450 and induction of heterocyclic amine DNA adducts in human liver samples in vivo and in vitro. Cancer Epidemiol. Biomarkers Prev., 13, 1071-1078.
3. Degawa, M., Kojima, M., Hishinuma, T. and Hashimoto, Y. (1985): Sex-dependent induction of hepatic enzymes for mutagenic activation of a tryptophan pyrolysate component, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]-indole, by feeding in mice. Cancer Res., 45, 96-102.
4. Degawa, M., Kojima, M., Sato, Y. and Hashimoto, Y. (1986): Induction of a high spin form of cytochrome P-448 in the rat liver microsomes by 4-aminoazobenzene derivatives. Biochem. Pharmacol., 35, 3565-3570.
5. Degawa, M., Hishinuma, T., Yoshida, H. and Hashimoto, Y. (1987): Species, sex and organ differences in induction of a cytochrome P-450 isozyme responsible for carcinogen activation: effects of dietary hepatocarcinogenic tryptophan pyrolysate components in mice and rats. Carcinogenesis, 8, 1913-1918.
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