LC-MS analyses of N-acetyl-p-benzoquinone imine-adducts of glutathione, cysteine, N-acetylcysteine, and albumin in a plasma sample: A case study from a patient with a rare acetaminophen-induced acute swelling rash-Reference-Cited by-同舟云学术

LC-MS analyses of N-acetyl-p-benzoquinone imine-adducts of glutathione, cysteine, N-acetylcysteine, and albumin in a plasma sample: A case study from a patient with a rare acetaminophen-induced acute swelling rash

Published:2019 Issue:8 Volume:44 Page:559-563
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Ozawa Masashi¹²,Kubo Takashi³⁴,Lee Seon Hwa¹³,Oe Tomoyuki¹³

Affiliation:

1. Department of Bio-analytical Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University

2. Current address: Kyowa Hakko Kirin Co., Ltd.

3. Department of Bio-analytical Chemistry, Faculty of Pharmaceutical Sciences, Tohoku University

4. Current address: Meiji Seika Pharma Co., Ltd.

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/44/8/44_559/_pdf

Reference19 articles.

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2. Colombo, G., Clerici, M., Giustarini, D., Rossi, R., Milzani, A. and Dalle-Donne, I. (2012): Redox albuminomics: oxidized albumin in human diseases. Antioxid. Redox Signal., 17, 1515-1527.

3. Dahlin, D.C., Miwa, G.T., Lu, A.Y. and Nelson, S.D. (1984): N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen. Proc. Natl. Acad. Sci. USA, 81, 1327-1331.

4. Damsten, M.C., Commandeur, J.N., Fidder, A., Hulst, A.G., Touw, D., Noort, D. and Vermeulen, N.P. (2007): Liquid chromatography/tandem mass spectrometry detection of covalent binding of acetaminophen to human serum albumin. Drug Metab. Dispos., 35, 1408-1417.

5. Dart, R.C., Kuffner, E.K. and Rumack, B.H. (2000): Treatment of pain or fever with paracetamol (acetaminophen) in the alcoholic patient: a systematic review. Am. J. Ther., 7, 123-134.

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