Detection of non-genotoxic hepatocarcinogens and prediction of their mechanism of action in rats using gene marker sets
Author:
Affiliation:
1. Department of Molecular Pathology, Osaka City University Graduate School of Medicine
2. Drug Safety Research Laboratories, Astellas Pharma Inc
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/41/2/41_281/_pdf
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4. Eichner, J., Wrzodek, C., Römer, M., Ellinger-Ziegelbauer, H. and Zell, A. (2014): Evaluation of toxicogenomics approaches for assessing the risk of nongenotoxic carcinogenicity in rat liver. PLoS One, 9, e97678.
5. Ellinger-Ziegelbauer, H., Gmuender, H., Bandenburg, A. and Ahr, H.J. (2008): Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies. Mutat. Res., 637, 23-39.
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