Effects of serial cervical or tail blood sampling on toxicity and toxicokinetic evaluation in rats
Author:
Affiliation:
1. Ajinomoto Co., Inc.
2. National Institute of Health Sciences
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/45/10/45_599/_pdf
Reference13 articles.
1. Caron, A., Lelong, C., Bartels, T., Dorchies, O., Gury, T., Chalier, C. and Benning, V. (2015): Clinical and anatomic pathology effects of serial blood sampling in rat toxicology studies, using conventional or microsampling methods. Regul. Toxicol. Pharmacol., 72, 429-439.
2. Diehl, K.H., Hull, R., Morton, D., Pfister, R., Rabemampianina, Y., Smith, D., Vidal, J.M. and van de Vorstenbosch, C.; European Federation of Pharmaceutical Industries Association and European Centre for the Validation of Alternative Methods. (2001): A good practice guide to the administration of substances and removal of blood, including routes and volumes. J. Appl. Toxicol., 21, 15-23.
3. Gram, L.F., Andreasen, P.B., Overo, K.F. and Christiansen, J. (1976): Comparison of single dose kinetics of imipramine, nortriptyline and antipyrine in man. Psychopharmacology (Berl.), 50, 21-27.
4. ICH. (1994): ICH S3A: Note for guidance on toxicokinetics: The assessment of systematic exposure in toxicity studies. (https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Safety/S3A/Step4/S3A_Guideline.pdf)
5. ICH. (2017): ICH S3A Q&A focus on microsampling. (https://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Safety/S3A/S3AIWG_Step4_2017_1116.pdf).
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