TWO-YEAR FEED STUDY OF CARCINOGENICITY AND CHRONIC TOXICITY OF ORTHO-CHLORONITROBENZENE IN RATS AND MICE

Author:

MATSUMOTO Michiharu1,UMEDA Yumi1,SENOH Hideki,SUZUKI Masaaki1,KANO Hirokazu1,KATAGIRI Taku1,AISO Shigetoshi1,YAMAZAKI Kazunori1,ARITO Heihaciro1,NAGANO Kasuke1,YAMAMOTO Seigo1,MATSUSHIMA Taijiro1

Affiliation:

1. Japan Bioassay Research Center, Japan Industrial Safety and Health Association

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Reference38 articles.

1. Bannasch, P., Griesemer, R.A., Anders, F., Becker, R., Cabral, J.R., Della Porta, G., Feron, V.J., Henschler, D., Ito, N., Kroes, R., Magee, P.N., McKnight, B., Mohr, U., Montesano, R., Napalkov, N.P., Nesnow, S., Pegg, A.E., Rao, G.N., Turusov, V.S., Wahrendorf, J. and Wilbourn, J. (1986): Long-term assays for carcinogenicity in animals. In Long-term and Short-term Assays for Carcinogens: A Critical Appraisal. (Montesano, R., Bartsch, H., Vainio, H., Wilbourn, J. and Yamasaki, H., eds.), IARC Scientific Publications No. 83, pp. 34-36, IARC, Lyon.

2. Booth, G. (2003): Chloronitrobenzenes. In Ullmann's Encyclopedia of Industrial Chemistry, 6th comp rev ed., Vol.23, (Wiley-VCH, ed.), pp.142-145. Wiley-VCH Verlag, Weinheim.

3. Bray, H.G., James, S.P. and Thorpe, W.V. (1956): The metabolism of the monochloronitrobenzenes in the rabbit. Biochem. J., 64, 38-44.

4. Butterworth, B.E., Popp, J.A., Conolly, R.B. and Goldsworthy, T.L. (1992): Chemically induced cell proliferation in carcinogenesis. In Mechanisms of Carcinogenesis in Risk Identification. (Vainio, H., Magee, P.N., McGregor, D.B. and McMichael, A.J., eds.), IARC Scientific Publications No. 116, pp. 279-305, IARC, Lyon.

5. Chemical Daily (2006): o-Chloronitrobenzene. In Chemical Products Handbook 14906. pp.927-928, The Chemical Daily Co. Ltd., Tokyo (in Japanese).

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