Decrease in protein binding and its effect on toxicokinetics (TK) / toxicodynamics (TD) of diclofenac and propranolol in pregnant rats
Author:
Affiliation:
1. Department of Geriatric Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Chiba University
2. Medicinal Safety Research Labs., Daiichi Sankyo Co., Ltd.
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
http://www.jstage.jst.go.jp/article/jts/33/5/33_5_525/_pdf
Reference18 articles.
1. Pregnancy-Induced Changes in Pharmacokinetics
2. Batra, V.K. (1995): Toxicokinetics/toxicodynamic correlations: goals, methods, and limitations. Toxicol. Pathol., 23, 158-164.
3. Clinical Pharmacokinetics of Diclofenac
4. Glezen, W.P. and Alpers, M. (1999): Maternal immunization. Clin. Infect. Dis., 28, 219-224.
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