Effective use of the <i>Pig-a</i> gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals-Reference-Cited by-同舟云学术

Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals

Published:2012 Issue:5 Volume:37 Page:943-955
ISSN:0388-1350
Container-title:The Journal of Toxicological Sciences
language:en
Short-container-title:J. Toxicol. Sci.

Author:

Kimoto Takafumi¹,Chikura Satsuki¹,Suzuki-Okada Kumiko¹,Kobayashi Xiao-mei¹,Itano Yasuhiro¹,Miura Daishiro¹,Kasahara Yoshinori¹

Affiliation:

1. TEIJIN Pharma Limited

Publisher

Japanese Society of Toxicology

Subject

Toxicology

Link

https://www.jstage.jst.go.jp/article/jts/37/5/37_943/_pdf

Reference38 articles.

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2. Cammerer, Z., Bhalli, J.A., Cao, X., Coffing, S.L., Dickinson, D., Dobo, K.L., Dobrovolsky, V.N., Engel, M., Fiedler, R.D., Gunther, W.C., Heflich, R.H., Pearce, M.G., Shaddock, J.G., Shutsky, T., Thiffeault, C.J. and Schuler, M. (2011): Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-comparison with other in vivo genotoxicity endpoints. Environ. Mol. Mutagen., 52, 721-730.

3. Casciano, D.A., Aidoo, A., Chen, T., Mittelstaedt, R.A., Manjanatha, M.G. and Heflich, R.H. (1999): Hprt mutant frequency and molecular analysis of Hprt mutations in rats treated with mutagenic carcinogens. Mutat. Res., 431, 389-395.

4. Dertinger, S.D., Bryce, S.M., Phonethepswath, S. and Avlasevich, S.L. (2011b): When pigs fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis. Mutat. Res., 721, 163-170.

5. Dertinger, S.D. and Heflich, R.H. (2011): In vivo assessment of Pig-a gene mutation-recent developments and assay validation. Environ. Mol. Mutagen., 52, 681-684.

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